Ressource Scientifique

Publication scientifique
28/03/2025

Publication: The Nature of Nanodisc Lipids Influences Fragment-Based Drug Discovery Results

Discover how nanodisc lipids impact fragment-based drug discovery, enhancing membrane protein screening and enabling new therapeutic possibilities.

Graphic example of a molecular glue
Blog
06/03/2025

Cooperativity: The Missing Link in Molecular Glue Discovery

In this Q&A, discover how cooperativity is unlocking new potential in molecular glues and enabling the targeting of previously “undruggable” proteins.

Scientist at the Oncodesign Services-ZoBio Group laboratory in Leiden, the Netherlands, works on a surface plasmon resonance (SPR) experiment.
Ressource Scientifique
03/03/2025

Case study: Capturing out-of-range target engagement kinetics for an advanceable clinical candidate

Characterizing the inhibition of PRMT5:MTA by MRTX1719, a clinical stage MTAP-deleted cancer therapeutic.

Medicinal Chemistry's Insights into the Microbiome
Blog
19/11/2024

Medicinal Chemist’s Insights into the Microbiome

Here, we highlight the need to consider early the microbiome in drug discovery, as it may influence drug responses, therefor efficacy

AI in drug discovery - Oncodesign Services
Blog
10/10/2024

The Game-Changing Role of Artificial Intelligence in Drug Discovery

Discover in this blog how Artificial Intelligence (AI) has a game-changing role in drug discovery and computational chemistry

Radionuclides: a sourcing challenge
Blog
24/09/2024

Radionuclides: a sourcing challenge

In this blog, we deal with overcoming radionuclides supply challenges with innovative solutions by Oncodesign Services

COVID-19 | New vaccine
Publication scientifique
13/05/2024

How Oncodesign Services contributed to the Development of a New COVID-19 Vaccine

Oncodesign Services provided valuable support in bioanalysis and dosage for the development on new vaccine against COVID-19.

Publication scientifique
07/05/2024

Meeting with Patrick Jimonet (Medicen)

In this interview, discover how Patrick Jimonet led and united over thirty prominent international experts to develop proposals aimed at facilitating the integration of the microbiome into drug discovery. 💊

WEBINAR - RNA modulation with small molecule'
Webinaire
24/04/2024

How to target RNA modulation with small molecule?

In this two-part free webinar series, we've assembled a team of leading experts who will delve into the intricacies of RNA modulation, explore its potential applications, and showcase real-world case studies.

Poster scientifique | Oncodesign Services
Poster
07/04/2024

Intra-cranial administration of MTL-004, a promising post-resection treatment for glioblastoma

Gliomas (GBM), are exceptionally hard to treat, aggressive and genetically heterogeneous tumors. Read the poster to discover the case study!

Poster scientifique | Oncodesign Services
Poster
07/04/2024

Evaluation of checkpoint inhibitor efficacy in a humanized immune system mouse model lacking murine Fc gamma receptors

Humanized immune system (HIS) mice are critical immuno-oncology tools for evaluating antibody-based therapeutic target engagement and efficacy in a human-like context

Poster scientifique | Oncodesign Services
Poster
07/04/2024

New technologies and capabilities supporting the development of novel Molecular RadioTherapy agents

Read our Oncodesign-Services' poster which provides cutting-edge technologies and products to support the development of radiopharmaceuticals for theranostics.