Examples of translational preclinical models to mimic cancer drug resistance

Resistance mechanisms are now well studied in vitro, based on mutated cell lines for specific resistance pathways. Discover our poster!

Next frontier in Cancer: Deep Dive into Oncolytic Viruses

In this blog, we pay attention in the development of oncolytic viruses (OVs) which destroy cancer cells and leverage the host immune system to enhance the effect.

Immunogenicity and efficacy of VLA2001 vaccine against SARS-CoV-2 infection in male cynomolgus macaques

Inactivated vaccines inducing durable cross-protective responses, safety and maintaining preparedness for future seasonally emerging SARS-CoV-2 variants

Advancing Pulmonary Fibrosis: Preclinical Readouts in Mice Models

Gut Microbiome Integration in Drug Discovery and Development of Small Molecules

More than 30 international leading experts has developed proposals to facilitate integration of the microbiome in drug discovery and development.

Phinc & Oncodesign Services

With Oncodesign Services and Phinc, unlocking the power of PBPK prediction and ADMET experimentation for a better drug development!

Advancing Drug Discovery through 3D Cell Models: Unveiling Novel Hits and Mechanisms

Discover our findings highlight the importance of 3D cell models in drug discovery. Download the poster!

Combitherapy in Preclinical Breast Cancer HR+/HER2- Models

Doublet and Triplet Combinations of Eribulin, Fulvestrant, and Palbociclib in Preclinical Breast Cancer Models

This study investigated in vivosynergism between eribulin and palbociclib in a breastcancer patient-derived xenograft (PDX) model.

Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer’s Disease Drug Candidate

How to repurpose your cancer drug to a Molecular RadioTherapy drug candidate

In this blog, Dr Eftychia Koumarianou deals with the ground-breaking and intriguing approach that hides behind the theranostics.

Chronic inflammation and cancer: how can preclinical models revolutionize our understanding?

Olivier Duchamp discusses the development of new anti-inflammatory strategies for the prevention and treatment of cancer using a better modeling