Scientific resource
Poster

Poster – Humanized mice in Immuno-Oncology : A game-changer for preclinical research
The poster include illustrative data and case study examples highlighting the platform and their use in preclinical studies

From Reactivity to Selectivity: Unlocking Covalent Screening
Scientific poster: discover how covalent compound library screening enables selective, progressable hits for PPIs, kinases, and other tough targets.

MTL-004, a promising new therapeutic for post-resection treatment of glioblastoma
MTL-004 was found to be safe and well-tolerated at a dose of 1 mg/kg, and was excreted mainly through urine. Read the poster!

TEQ103, a novel therapeutic for the treatment of breast cancer
These results demonstrate the significant durable antitumor effect of TEQ103 driven by the total dose administered. Read the poster!

Metastasis Development Induced by Intracarotid Injection
We show a new TNBC mouse model of brain metastasis, induced by intracarotid injection, while assessing BBB integrity. Read the poster!

Pharmacological evaluation using the AbYlink TM regio-selective conjugation technology
AbYlink is a regio-selective labeling method, enabling a one-step conjugation of payloads to the Fc domain of an antibody. Read the poster!

Novel PSMA+ and FAP+ mouse models
We designed new mouse models, which could aid in the development of novel imaging or radiotherapy agents for two biomarkers. Read the poster!

PDX-Derived Organoids: Insights into Cancer Stem Cells and Metastasis
Our study highlights the versatility and translational relevance of PDXOs in cancer research. Read the poster!

Intra-cranial administration of MTL-004, a promising post-resection treatment for glioblastoma
Gliomas (GBM), are exceptionally hard to treat, aggressive and genetically heterogeneous tumors. Read the poster to discover the case study!

Evaluation of checkpoint inhibitor efficacy in a humanized immune system mouse model lacking murine Fc gamma receptors
Humanized immune system (HIS) mice are critical immuno-oncology tools for evaluating antibody-based therapeutic target engagement and efficacy in a human-like context

New technologies and capabilities supporting the development of novel Molecular RadioTherapy agents
Read our Oncodesign-Services' poster which provides cutting-edge technologies and products to support the development of radiopharmaceuticals for theranostics.

Examples of translational preclinical models to mimic cancer drug resistance
Resistance mechanisms are now well studied in vitro, based on mutated cell lines for specific resistance pathways. Discover our poster!