Oncodesign Services - Biologics

DRIVE-Biologics

Circle Oncodesign Services

A premium experts ecosystem to support your biologics drug discovery & development

DRIVE-Biologics leverages the skills and expertise to develop antibodies in oncology and inflammation through a close collaboration with Abzena.

Oncodesign Services provides an unique integrated solution to access market analysis, and establish the ability to design, optimize and develop novel biological entities addressing the therapeutic target of interest.

Biologics discovery & development requires client-driven & flexible specialties companies

 

DRIVE-Biologics supplies the high-level, IND-focused discipline to rigorously manage the integrated programs from the early stages of discovery through to preclinical development, CMC & manufacturing.

  • Target ID and validation
    • Reagent cell line generation
    • Proteomics
    • Protein biophysics
    • In vitro model generation
    • In vivo model generation
    • Tool identification
    • siRNA
  • Discovery
    • Antibody discovery
    • Material supply (transients)
    • ADC proof of concept
  • Lead Optimization
    • Candidate optimization
    • Developability cascade to ensure optimal candidate selection
    • Bioconjugation design & optimization
    • In vitro biology (primary cell lines)
    • In vitro and in vivo DMPK 
    • Radiolabeling
    • Imaging biodistribution 
  • Preclinical development
    • Cell Line development
    • Material supply (stable pools)
    • Formulation development
    • Process development
    • GMP manufacture of biologics and ADCs
    • In vivo pharmacology 
    • In vitro and in vivo DMPK 
    • Efficacy proof of concept
    • Pharmaco-imaging
    • PK & time activity Curves 
    • Regulatory support

A strong alliance of experts

Do you want to know more about our cababilities for biologics? Contact-us!

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