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Scientific resource
16/06/2025

How Humanized Models Advance Oncology Drug Development

A Q&A with Caroline on how humanized models have emerged as a game-changing tool in preclinical research.

Abstract render of glowing blue cells in microscopic view
Blog
10/06/2025

What Can Engineered Cells Tell You About Your Compound?

From signaling to surprises, reporter cell assays bring clarity to compound screening. Read the blog to find out what engineered cells can tell you.

Representing radioligand binding assays (RLBA), an assay plate in neon pink.
Blog
23/04/2025

Radioligand Binding Assays: A Lost Art in Drug Discovery?

Old-school or still essential? Explore the overlooked power of radioligand binding assays in today's research environment.

Scientific publication
28/03/2025

Publication: The Nature of Nanodisc Lipids Influences Fragment-Based Drug Discovery Results

Discover how nanodisc lipids impact fragment-based drug discovery, enhancing membrane protein screening and enabling new therapeutic possibilities.

Graphic example of a molecular glue
Blog
06/03/2025

Cooperativity: The Missing Link in Molecular Glue Discovery

In this Q&A, discover how cooperativity is unlocking new potential in molecular glues and enabling the targeting of previously “undruggable” proteins.

Scientist at the Oncodesign Services-ZoBio Group laboratory in Leiden, the Netherlands, works on a surface plasmon resonance (SPR) experiment.
Scientific resource
03/03/2025

Case study: Capturing out-of-range target engagement kinetics for an advanceable clinical candidate

Characterizing the inhibition of PRMT5:MTA by MRTX1719, a clinical stage MTAP-deleted cancer therapeutic.

Medicinal Chemistry's Insights into the Microbiome
Blog
19/11/2024

Medicinal Chemist’s Insights into the Microbiome

Here, we highlight the need to consider early the microbiome in drug discovery, as it may influence drug responses, therefor efficacy

AI in drug discovery - Oncodesign Services
Blog
10/10/2024

The Game-Changing Role of Artificial Intelligence in Drug Discovery

Discover in this blog how Artificial Intelligence (AI) has a game-changing role in drug discovery and computational chemistry

Radionuclides: a sourcing challenge
Blog
24/09/2024

Radionuclides: a sourcing challenge

In this blog, we deal with overcoming radionuclides supply challenges with innovative solutions by Oncodesign Services

Oncolytic virus - Blog
Blog
03/04/2024

Next frontier in cancer: deep dive into oncolytic viruses

In this blog, we pay attention in the development of oncolytic viruses (OVs) which destroy cancer cells and leverage the host immune system to enhance the effect.

Blog
01/12/2023

How to repurpose your cancer drug to a Molecular RadioTherapy drug candidate

In this blog, Dr Eftychia Koumarianou deals with the ground-breaking and intriguing approach that hides behind the theranostics.

Blog
17/10/2023

Targeted RNA degradation: Principle and Therapeutic Promises

RNA, or RiboNucleic Acid, is a structured macromolecule which plays a central role in numerous cellular functions.