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How Humanized Models Advance Oncology Drug Development
A Q&A with Caroline on how humanized models have emerged as a game-changing tool in preclinical research.

What Can Engineered Cells Tell You About Your Compound?
From signaling to surprises, reporter cell assays bring clarity to compound screening. Read the blog to find out what engineered cells can tell you.

Radioligand Binding Assays: A Lost Art in Drug Discovery?
Old-school or still essential? Explore the overlooked power of radioligand binding assays in today's research environment.

Publication: The Nature of Nanodisc Lipids Influences Fragment-Based Drug Discovery Results
Discover how nanodisc lipids impact fragment-based drug discovery, enhancing membrane protein screening and enabling new therapeutic possibilities.

Cooperativity: The Missing Link in Molecular Glue Discovery
In this Q&A, discover how cooperativity is unlocking new potential in molecular glues and enabling the targeting of previously “undruggable” proteins.

Case study: Capturing out-of-range target engagement kinetics for an advanceable clinical candidate
Characterizing the inhibition of PRMT5:MTA by MRTX1719, a clinical stage MTAP-deleted cancer therapeutic.

Medicinal Chemist’s Insights into the Microbiome
Here, we highlight the need to consider early the microbiome in drug discovery, as it may influence drug responses, therefor efficacy

The Game-Changing Role of Artificial Intelligence in Drug Discovery
Discover in this blog how Artificial Intelligence (AI) has a game-changing role in drug discovery and computational chemistry

Radionuclides: a sourcing challenge
In this blog, we deal with overcoming radionuclides supply challenges with innovative solutions by Oncodesign Services

Next frontier in cancer: deep dive into oncolytic viruses
In this blog, we pay attention in the development of oncolytic viruses (OVs) which destroy cancer cells and leverage the host immune system to enhance the effect.

How to repurpose your cancer drug to a Molecular RadioTherapy drug candidate
In this blog, Dr Eftychia Koumarianou deals with the ground-breaking and intriguing approach that hides behind the theranostics.

Targeted RNA degradation: Principle and Therapeutic Promises
RNA, or RiboNucleic Acid, is a structured macromolecule which plays a central role in numerous cellular functions.