Inflammation is normally a protective response that eliminates harmful stimuli and restores tissue homeostasis. But it is now well established that unresolved chronic inflammation caused by persistent infection, external injury, metabolic disorders or autoimmune diseases can lead to the initiation and development of cancers.
Recently, it is estimated that around 20 to 25% of cancer cases are linked to chronic inflammation. Better evidence of the role of inflammatory processes in cancer initiation, promotion, progression, angiogenesis and metastasis will clearly help in the development of new anti-inflammatory strategies for cancer prevention and treatment.
In this publication on Labiotech.eu, Olivier Duchamp highlights that a better understanding and modeling of the chronic inflammation process could help develop new anti-inflammatory strategies for the prevention and treatment of cancer.