In vivo imaging modalities to accelerate the time-to-market of your candidate
With 25 years of experience, Oncodesign Services is your partner for your preclinical studies based on in vitro and in vivo models combined with non-invasive imaging technologies.
Introduction to in vivo imaging
In vivo imaging refers to the visualization and analysis of biological processes within a living organism. This technique allows researchers to study and monitor various physiological and pathological events in real-time, providing valuable insights into the functioning of biological systems.
In the context of drug development IND enabling preclinical studies, in vivo imaging is a powerful tool used in laboratory animals, such as mice or rats, to investigate disease progression, evaluate the efficacy of treatments, and understand the underlying mechanisms of various conditions.
What are the key benefits of in vivo imaging in Drug Development?
Key reasons why in vivo imaging is utilized in preclinical studies include:
- Non-invasive technology
- Decreasenumber of animals
- Real-time tumor monitoring
- Provider of quantitative and qualitative data to support the IND enabling package
- Early and predictive evaluation of drug potency
Common modalities used for in vivo imaging studies
Common modalities used in in vivo imaging for preclinical studies include:
- Nuclear Imaging
- positron emission tomography (PET)
- Single-photon emission computed tomography (SPECT)
- Magnetic Resonance Imaging (MRI)
- Computed Tomography (CT)
- Optical Imaging
- bioluminescence imaging
- fluorescence imaging
- Ultrasound
Each technique has its strengths and limitations, and researchers often choose the most suitable method based on the specific requirements of their study.
Oncodesign Services, your partner for you in vivo imaging studies
Oncodesign Services provides state-of-the-art in vivo imaging services combined with translational pharmacology services. Our pharmacology platform intergrated along the years imaging multimodalities:
- MRI 4.7T
- Nuclear imaging (PET/CT, SPECT/CT, PET/MR)
- Optical imaging (Bioluminescence, Fluorescence)
- Ultrasound
Oncodesign Services’ in vivo multi-modal imaging platform can be used for biodistribution studies, tumor volume tracking and to assess mechanism of action .
