Deciphering the Microbiome’s role in drug discovery with an experienced CRO
Why studying and understanding the human microbiome is important in drug discovery?
The human microbiome refers to the trillions of microorganisms, including bacteria, viruses, fungi, and archaea, that inhabit various regions of the body, such as the gastrointestinal tract, skin, oral cavity, and more. Having a profound influence on human health and disease but also on efficiency of non-microbial drugs, taking the human microbiome into account is becoming crucial for the development of innovative therapies.
Efforts were made to harness the microbiome for diagnostic and prophylactic/therapeutic purposes. The microbiome research can include:
- Study the relationship between microbiome composition and the disease of interest
- Evaluation of microbiome therapeutics
- Definition of the role of microbiome in precision diagnosis and personalized treatment
- Understanding the impact of a drug on microbiome & the influence of microbiome on individual’s response to a drug
Harnessing the microbiome in drug discovery with Oncodesign Services
Oncodesign Services has developed a comprehensive platform to demonstrate the benefit on health, to assess safety and/or to decipher mechanism(s) of action of microbiome-based therapeutics or non-microbial drugs.
We use a broad range of technological approaches for culturing, detecting, identifying and localizing microorganisms (bacteria, yeasts, etc.) in simple or complex samples (fluids, tissues) coming from preclinical studies or clinical trials.