Accelerate the timeline of your drug discovery project with our drug candidate selection program
Developing a new drug is based on the selection of molecules of interest called “candidate” having a therapeutic effect on the target. For that, pharmaceutical companies must respect some key preclinical stages of the drug discovery process, from target identification to lead optimization.
Oncodesign Services, a leading CRO in early drug discovery, guides you to success on your drug candidate selection.
What is the drug candidate selection process ?
Drug candidate selection is the process of identifying potential new drugs that can be developed to treat a specific disease. This process involves several stages, including target identification, lead discovery, lead optimization, and preclinical testing.
Target identification involves identifying a specific molecular target that is involved in the disease process, such as a protein or enzyme. Hit identification involves identifying compounds that can interact with the target and potentially inhibit or modulate its activity. Lead optimization involves further refining the structure of the lead compound to improve its potency, selectivity, and other drug-like properties.
Once a promising drug candidate has been identified, it undergoes preclinical testing to evaluate its safety and efficacy in animal models. This testing involves a range of studies, including pharmacokinetics (how the drug is absorbed, distributed, metabolized, and eliminated in the body), toxicology (the potential for the drug to cause harm), and efficacy (how well the drug works in treating the disease).
After preclinical testing, if a drug candidate is deemed safe and effective, it can proceed to clinical trials in humans.
Oncodesign Services offers an integrated solution for your Drug Candidate selection
Expert in translational sciences, our experienced scientific teams in drug metabolism and pharmacokinetics (DMPK/ADME) will help you to establish in-vitro, in-vivo and PK/PD correlations and predictions of human dose for promising candidates.
All the along drug candidate selection, from target identification to lead optimization, the company contributes to the development of innovative therapies in oncology, inflammation and infectious diseases, with high medical needs.
Our Drug candidate selection programs include :
Structure based drug design/Molecular Modelling
Multi-parameter optimization – AI
Multi-species PK & Allometric scaling
Early Scale-up and formulation
Early Safety assessment
Why choose Oncodesign Services for your drug candidate selection programs?
- A multidisciplinary team with 25 years of experience in Drug Discovery
- All analytical capabilities in a unique company
- A dedicated project leader as single point of contact
- Expertise in key therapeutic areas (oncology, inflammation, infectious diseases…)
Learn more about our services for Drug candidate selection ? Contact Us !