Tumor models in oncology

Circle Oncodesign Services

Discover a wide selection of tumor and cancer models in oncology

 

Oncodesign Services, a CRO specialized in Drug Discovery, offers a range of discovery and preclinical services built upon cancer models of syngeneic, cell-derived xenograft (CDX) and patient-derived xenograft (PDX) tumors.

With individual or integrated studies, we contribute to the discovery of innovatives therapies against cancer.

Discover our services in oncology

Standard readouts in oncology

◈ Tumor size

◈ Liquid biopsy

◈ Protein expression

◈ Cytokine/biomarker expression (by LBA)

◈ TIL fractions (by flow/FACS)

◈ Histology

◈ Conservation of phenotype and genotype

◈ Gene expression stability

◈ Gene mutation status

◈ Response to standard of care (SOC)

Over 500 tumor models for translational research

Over 500 syngeneic, CDX and PDX tumor models are established in-house, covering 20 organ origins and up to 35 pathologies. These cover solid tumors, hematological malignancies and metastasis models.

Integrated CRO services in Oncology

Oncodesign Services encompasses all preclinical services to deliver cancer drug candidates including:

2

Bioanalysis

Bioanalysis for Oncology

Oncodesign Services offers formulation, immunogenicity and bioanalytical sample analysis services including platforms for small molecules (NCEs), peptides, large molecules (NBEs), monoclonal antibodies (mAb), Antibody-Drug Conjugates (ADC), Anti-Drug Antibodies (ADA), Neutralizing Antibodies (Nab), oligonucleotides (OGN) and biomarkers (simplex/multiplex).

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3

In vitro biology

In vitro biology for Oncology

Oncodesign Services offers both off-the-shell assays using commercial kits and in-house developed assays with customized reagent panels.

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4

Pharmaco-Imaging

Pharmaco-Imaging for Oncology

Discover Oncodesign Services’in vivo multi-modal imaging platform for non-invasive studies to support proof of concept in pharmacology.

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5

DMPK

DMPK for Oncology

Oncodesign Services studies the pharmacokinetics and metabolism of your new therapeutic entities.

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6

In vivo pharmacology

In vivo pharmacology for Oncology

From its inception, Oncodesign Services has dedicated efforts to centralize skills, assays and expertise to conduct complete preclinical pharmacological characterization of drugs in the field of oncology, immunology, immune-inflammation or infectious diseases. Our multi-disciplinary team keeps your program moving quickly by providing proof of concept for your lead compounds.

READ MORE

Bioanalysis for Oncology

Oncodesign Services offers formulation, immunogenicity and bioanalytical sample analysis services including platforms for small molecules (NCEs), peptides, large molecules (NBEs), monoclonal antibodies (mAb), Antibody-Drug Conjugates (ADC), Anti-Drug Antibodies (ADA), Neutralizing Antibodies (Nab), oligonucleotides (OGN) and biomarkers (simplex/multiplex).

READ MORE

In vitro biology for Oncology

Oncodesign Services offers both off-the-shell assays using commercial kits and in-house developed assays with customized reagent panels.

READ MORE

Pharmaco-Imaging for Oncology

Discover Oncodesign Services’in vivo multi-modal imaging platform for non-invasive studies to support proof of concept in pharmacology.

READ MORE

DMPK for Oncology

Oncodesign Services studies the pharmacokinetics and metabolism of your new therapeutic entities.

READ MORE

In vivo pharmacology for Oncology

From its inception, Oncodesign Services has dedicated efforts to centralize skills, assays and expertise to conduct complete preclinical pharmacological characterization of drugs in the field of oncology, immunology, immune-inflammation or infectious diseases. Our multi-disciplinary team keeps your program moving quickly by providing proof of concept for your lead compounds.

READ MORE

Oncodesign Services - Paris

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Circle Oncodesign Services