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ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance
Read in Communication Biologics (Nature), the data from the exoSTING preclinical program, in which Oncodesign participated (Hepa1-6).

Pharmacokinetic and Biodistribution of Formatted Affimer® Biotherapeutics Targeting PD-L1
Programmed Cell Death-Ligand 1 (PD-L1) is part of the immune checkpoint system involved in preventing autoimmunity. PD-L1 is upregulated on tumors cells and binds to its receptor, PD-1, expressed by immune cells in the tumor microenvironment.

Tumor-specific molecular changes in luminal B breast cancer patient-derived xenografts (PDXs) with acquired resistance to endocrine treatment
In this study we describe establishment of a luminal breast cancer PDX model with acquired resistance to hormonotherapy

Antitumor Activity of Eribulin After Fulvestrant Plus CDK4/6 Inhibitor in Breast Cancer Patient-derived Xenograft Models
Antitumor Activity of Eribulin After Fulvestrant Plus CDK4/6 Inhibitor in Breast Cancer Patient-derived Xenograft Models

Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection

Development of an immunogenicity assay for Anti Drug Antibody (ADA)
Immunogenicity assessement for the detection of ADA (Anti Drug Antibody) directed against CpG-D35 using ECL technology (MSD) in serum samples.

[EN] MRI: going beneath the surface in preclinical oncology
MRI allows easier tumor growth monitoring in preclinical oncology combining benefits of orthotopic models and regular subcutaneous models.